4-Chlorophenylboronic acid CAS 1679-18-1: A Buyer’s Guide to Specifications, COA, SDS, and Bulk Supply

Author: Ada

Sep. 15, 2026

Chemicals

4-Chlorophenylboronic Acid CAS 1679-18-1: A Buyer’s Guide to Specifications, COA, SDS, and Bulk Supply

If you are sourcing 4-Chlorophenylboronic acid, CAS 1679-18-1, the most important checks are identity, assay, impurity profile, documentation, packaging, and supply continuity. I recommend evaluating the product from both a technical and procurement perspective rather than relying on a single purity number. At Maison Chemical, we support B2B buyers by organizing product specifications, batch-related quality documents, safety information, and bulk supply discussions according to the intended application.

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4-Chlorophenylboronic acid is an aromatic boronic acid commonly considered as a building block for synthetic chemistry and pharmaceutical intermediate development. Its molecular formula is commonly represented as C6H6BClO2, with a molecular weight of approximately 156.37 g/mol. Because actual release specifications can vary by supplier, grade, and application, buyers should confirm every critical parameter in the current specification sheet and batch COA.

Who This Guide Is For

This guide is intended for pharmaceutical intermediate manufacturers, medicinal chemistry teams, contract research organizations, process development groups, chemical distributors, and purchasing departments. It is especially useful when a buyer needs more than a catalog description and must compare documentation, quality controls, packaging, and production availability. The same evaluation framework can also support import, registration, and internal supplier-approval workflows.

I have written this guide for buyers who need to prepare a compliant inquiry for 4-Chlorophenylboronic acid CAS 1679-18-1. It does not replace the product-specific SDS, technical data sheet, or internal risk assessment. Instead, it provides a practical structure for asking the right questions before placing a sample or bulk order.

What the Product Is and Why It Is Purchased

4-Chlorophenylboronic acid is an organoboron compound containing a chlorinated aromatic ring and a boronic acid functional group. In synthetic chemistry, boronic acids are often selected as reaction partners in carbon–carbon bond-forming processes, including Suzuki-type coupling routes, subject to the reaction design and the customer’s validated process. The compound may therefore be evaluated as a pharmaceutical intermediate building block, research reagent, or process-development raw material.

The product’s value depends on more than chemical identity. Water content, residual solvents, inorganic residues, unreacted starting materials, regioisomeric impurities, and decomposition-related impurities may influence downstream reaction performance. For this reason, a buyer should define which parameters are critical to quality before comparing quotations.

Key Specifications Buyers Should Review

Identity and Core Physical Information

Parameter What the Buyer Should Confirm
Product name 4-Chlorophenylboronic acid
CAS number 1679-18-1
Molecular formula C6H6BClO2, subject to supplier confirmation
Molecular weight Approximately 156.37 g/mol
Appearance Supplier-defined description, such as solid or powder characteristics
Assay Specify the analytical method, reporting basis, and acceptance limit
Water and residual solvents Confirm whether these are tested and how results are reported

The molecular weight is useful for process calculations but should not be treated as a purity result. For example, 1.00 mol corresponds theoretically to approximately 156.37 g of material before considering assay, water, and other impurities. If a buyer orders 100 g, the nominal amount is approximately 0.639 mol based on molecular weight alone; the actual effective amount depends on the reported assay and moisture content.

Assay and Impurity Profile

Assay is usually one of the first comparison points, but a high assay value does not automatically prove that two suppliers offer equivalent material. I recommend requesting the assay method, chromatographic conditions or method reference where available, and the individual or total impurity limits. Buyers developing a sensitive route may also need information on palladium, other metals, halides, residual solvents, and water.

Not every parameter is relevant to every project, so the specification should match the intended use. A research-stage buyer may prioritize availability and a standard COA, while a commercial process may require tighter impurity controls, defined retest practices, change notification, and lot traceability. Maison Chemical can review the target specification before quotation so that the commercial offer reflects the actual requirement.

How to Read a COA for CAS 1679-18-1

A Certificate of Analysis should be connected to a specific production batch rather than presented as a generic marketing document. I suggest checking the batch number, manufacturing or analysis date where provided, test methods, results, specification limits, and approval status. The document should clearly identify the material as 4-Chlorophenylboronic acid CAS 1679-18-1.

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COA Checklist

  • Product name and CAS number match the purchase request.
  • Batch or lot number is clearly stated.
  • Assay result is reported with a defined method or basis.
  • Appearance and identity tests are included where applicable.
  • Moisture, residual solvents, metals, or specific impurities are addressed when required.
  • The document includes an authorized quality review or release statement.
  • The COA specification matches the agreed quotation and purchase order.

I advise buyers not to compare only the headline assay. Two COAs may use different analytical methods, reporting bases, or impurity panels, making direct comparison misleading. If the material will enter a regulated or customer-controlled process, the buyer should ask whether the supplier can provide a representative batch COA before order confirmation, subject to availability and commercial policy.

How to Use the SDS in Supplier Evaluation

The Safety Data Sheet supports hazard communication, transportation planning, storage review, and workplace handling decisions. It should be specific to the product and supplier, and it should be reviewed by the buyer’s qualified safety or regulatory personnel. The SDS is not a substitute for process safety assessment, because laboratory and manufacturing conditions can create risks beyond the information shown in a general document.

SDS Items to Confirm

  • Product identification and supplier contact details.
  • Hazard classification and precautionary statements.
  • Composition information.
  • First-aid, firefighting, accidental-release, and handling guidance.
  • Storage conditions and incompatibility information.
  • Exposure controls and personal protective equipment guidance.
  • Transport, disposal, and regulatory information where applicable.

Storage instructions should follow the current SDS and the supplier’s product documentation rather than an assumed temperature range. Buyers should also confirm whether the product is supplied in an inner bag, bottle, drum, or other packaging format, and whether the packaging protects the material from moisture or contamination during normal logistics.

Choosing the Right Supply Format

The appropriate supply format depends on consumption, validation status, and the cost of quality controls. Small quantities may be suitable for route screening, while larger quantities require stronger attention to batch consistency, packaging integrity, production scheduling, and freight arrangements. I recommend separating the sample evaluation decision from the long-term supply decision, because a successful sample does not by itself establish commercial continuity.

Buying Situation Recommended Focus
Early research Identity, standard COA, SDS, sample availability, and technical fit
Process development Impurity profile, moisture, batch reproducibility, and packaging
Commercial preparation Approved specification, supply capacity, lead time, change control, and logistics
Distribution Documentation package, labeling, export requirements, and lot traceability

Pricing, MOQ, and Lead-Time Questions

Pricing for 4-Chlorophenylboronic acid CAS 1679-18-1 can depend on quantity, specification, packaging, testing requirements, delivery destination, and order frequency. A quotation without a defined grade or specification may not be comparable with another supplier’s offer. Buyers should therefore state the requested quantity, target purity, documentation requirements, packing preference, destination, and desired delivery window.

MOQ and lead time should be confirmed for each order rather than assumed from a website listing. The practical lead time may differ between an available batch, a scheduled production lot, and a custom specification. Maison Chemical can discuss sample quantities, bulk requirements, documentation, packaging, and export arrangements according to the project stage.

Supplier Evaluation Checklist

Technical and Quality Questions

  1. Can the supplier confirm the identity and CAS number?
  2. Is a batch-specific COA available for review?
  3. Which assay and impurity methods are used?
  4. Can the supplier address moisture, residual solvents, metals, or other critical attributes?
  5. Are packaging, labeling, and lot traceability clearly defined?

Commercial and Service Questions

  1. What quantity can be supplied for the sample and bulk stages?
  2. What are the MOQ, lead time, and quotation validity conditions?
  3. Can the supplier support repeat orders with an agreed specification?
  4. How are specification changes or production changes communicated?
  5. Can the supplier coordinate export documents and delivery requirements?

I recommend sending one structured inquiry rather than several incomplete messages. Include CAS 1679-18-1, required quantity, target assay, critical impurities, packaging, destination, COA and SDS needs, and timing. This gives the supplier enough information to respond with a more useful and technically relevant proposal.

Summary of Key Takeaways

  • 4-Chlorophenylboronic acid CAS 1679-18-1 is an aromatic boronic acid used as a synthetic building block, subject to route and application requirements.
  • The commonly stated molecular weight is approximately 156.37 g/mol, but molecular weight is not a substitute for assay testing.
  • A reliable COA should be batch-specific and include defined test results, methods, limits, and release information.
  • The SDS should be current, product-specific, and reviewed together with the buyer’s own safety procedures.
  • Bulk purchasing decisions should include specification control, packaging, MOQ, lead time, traceability, and supply continuity.

Conclusion: A Practical Next Step for Buyers

The best way to evaluate 4-Chlorophenylboronic acid CAS 1679-18-1 is to compare the complete quality and supply package, not just the listed price or assay percentage. First define your application and critical quality attributes, then request the relevant specification, batch COA, SDS, packaging information, MOQ, lead time, and commercial terms. This approach reduces avoidable sourcing risk and makes supplier comparisons more meaningful.

Maison Chemical supports B2B inquiries for 4-Chlorophenylboronic acid as a manufacturer, supplier, and exporter of chemical products and pharmaceutical intermediates. Send us your required quantity, target specification, destination, and documentation needs, and we can assess the appropriate supply option for your project and provide a quotation for review.

Want more information on 4-Chlorophenylboronic acid CAS 1679-18-1? Feel free to contact us.

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